Johan W R Nortier Selected Research

telatinib

2/2011	Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors.
9/2009	Phase I dose escalation study of telatinib, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor 2 and 3, platelet-derived growth factor receptor beta, and c-Kit, in patients with advanced or metastatic solid tumors.

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Johan W R Nortier Research Topics

Disease

29	Breast Neoplasms (Breast Cancer) 01/2022 - 01/2009
23	Neoplasms (Cancer) 01/2020 - 01/2003
4	Alopecia (Baldness) 05/2019 - 01/2013
4	Colorectal Neoplasms (Colorectal Cancer) 07/2013 - 01/2006
3	Ovarian Neoplasms (Ovarian Cancer) 04/2013 - 01/2012
3	Melanoma (Melanoma, Malignant) 07/2012 - 07/2008
3	Nausea 01/2012 - 09/2009
2	Cognitive Dysfunction 04/2015 - 07/2013
2	Malnutrition (Nutritional Deficiencies) 04/2015 - 07/2013
2	Frailty 04/2015 - 07/2013
2	Disease Progression 09/2014 - 01/2012
2	Neoplasm Metastasis (Metastasis) 04/2014 - 07/2008
2	Vomiting 01/2012 - 02/2011
2	Ovarian Epithelial Carcinoma 01/2012 - 01/2012
2	Hypertension (High Blood Pressure) 01/2011 - 09/2009
2	Anemia 01/2006 - 01/2003
1	Dyspepsia (Indigestion) 01/2022
1	Osteonecrosis (Kienbock's Disease) 01/2022
1	Circulating Neoplastic Cells 03/2015
1	Unilateral Breast Neoplasms 02/2014
1	Margins of Excision 02/2014
1	Hot Flashes 01/2014
1	Chronic Disease (Chronic Diseases) 12/2013
1	Infertility (Sterility) 09/2013
1	Colitis 07/2012
1	Ascites 01/2012
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2011
1	Prostatic Neoplasms (Prostate Cancer) 06/2010
1	Neutropenia 10/2009

Drug/Important Bio-Agent (IBA)

11	Hormones (Hormone)IBA 01/2019 - 01/2011
10	exemestane (Aromasin)FDA Link 01/2019 - 01/2011
10	Tamoxifen FDA LinkGeneric 01/2019 - 01/2009
3	Hemoglobins (Hemoglobin)IBA 04/2015 - 01/2003
3	Cisplatin (Platino)FDA LinkGeneric 04/2013 - 04/2011
3	PlatinumIBA 04/2013 - 01/2006
3	Tyrosine Kinase InhibitorsIBA 02/2011 - 02/2007
2	Estrogen ReceptorsIBA 01/2022 - 01/2014
2	Diphosphonates (Bisphosphonates)IBA 01/2022 - 01/2019
2	Docetaxel (Taxotere)FDA Link 01/2019 - 01/2016
2	Letrozole (Femara)FDA LinkGeneric 01/2018 - 01/2018
2	Aromatase InhibitorsIBA 01/2018 - 01/2011
2	Indicators and Reagents (Reagents)IBA 04/2015 - 07/2013
2	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2014 - 01/2009
2	ErbB Receptors (EGF Receptor)IBA 12/2013 - 07/2013
2	Interleukin-6 (Interleukin 6)IBA 04/2013 - 01/2012
2	Carboplatin (JM8)FDA LinkGeneric 04/2013 - 01/2012
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 05/2011 - 03/2009
2	Melphalan (Alkeran)FDA LinkGeneric 05/2011 - 07/2008
2	telatinibIBA 02/2011 - 09/2009
2	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 02/2011 - 09/2009
2	DNA (Deoxyribonucleic Acid)IBA 06/2010 - 01/2009
1	Ibandronic Acid (Boniva)FDA Link 01/2022
1	AnthracyclinesIBA 05/2019
1	Zoledronic Acid (Zometa)FDA Link 01/2019
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2019
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019
1	Complement System Proteins (Complement)IBA 04/2018
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 04/2015
1	AlbuminsIBA 04/2015
1	CreatinineIBA 04/2015
1	Epithelial Cell Adhesion MoleculeIBA 03/2015
1	Estrogens (Estrogen)FDA Link 01/2014
1	EnzymesIBA 01/2014
1	Prostaglandins EIBA 04/2013
1	InterleukinsIBA 04/2013
1	AntibodiesIBA 04/2013
1	Dinoprostone (PGE2)FDA Link 04/2013
1	IpilimumabIBA 07/2012
1	Bevacizumab (Avastin)FDA Link 01/2012
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 01/2012
1	AntiemeticsIBA 01/2012
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2012
1	Biomarkers (Surrogate Marker)IBA 01/2012
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2012
1	Gemcitabine FDA Link 01/2012
1	CytokinesIBA 07/2011
1	Interferon-alpha (Interferon Alfa)IBA 07/2011
1	BenzodiazepinesIBA 02/2011
1	Dopamine AntagonistsIBA 02/2011
1	Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA 02/2011
1	E2F Transcription FactorsIBA 06/2010
1	E2F1 Transcription FactorIBA 06/2010
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 05/2010
1	Biological ProductsIBA 05/2010
1	Cytochrome P-450 CYP2D6 InhibitorsIBA 05/2010
1	Aurora KinasesIBA 10/2009
1	danusertibIBA 10/2009
1	Pharmaceutical PreparationsIBA 09/2009
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 09/2009

Therapy/Procedure

24	Therapeutics 01/2022 - 01/2003
19	Drug Therapy (Chemotherapy) 01/2020 - 01/2006
5	Adjuvant Chemotherapy 05/2019 - 02/2012
3	Neoadjuvant Therapy 01/2020 - 03/2015
1	Lymph Node Excision (Lymph Node Dissection) 01/2015
1	Aftercare (After-Treatment) 01/2015
1	Mastectomy (Mammectomy) 02/2014
1	Segmental Mastectomy (Lumpectomy) 02/2014
1	Radiotherapy 02/2014
1	Combination Drug Therapy (Combination Chemotherapy) 01/2012
1	Injections 07/2011